Chemical analysis, antimalarial and antioxidant activities, and cytotoxicity against human breast cancer cells volume. The aim of this study was to consider antibacterial effects of the methanolic extract of different parts of p. It was found that there is no correlation between phenolic content and antibacterial activity, similar results were obtained by turkmen et al. Antibacterial and antifungal activity from seed extracts of peganum harmala. Chemical composition, antibacterial and phytotoxic activities. Assessment of the antimicrobial and antioxidant activities. The aim of this study is to assess the antibacterial activity of alkaloids extracts from the seeds and roots of p. Antibacterial activity and conjugate investigation. Antibacterial activity of espand peganum harmala alcoholic extracts against six pathogenic bacteria in planktonic 111 of p. Experimental and computational study of biological activities.
The roots of the plant can reach a depth of up to 6. In this paper we studied the composition of the essential oils from p. Activity of peganum harmala extract against antibiotic. Microbial biofilms have attracted interest in recent years because they have become the most important cause of nosocomial infections. Phytochemical screening and evaluation of analgesic, anti. Antibacterial activity of espand peganum harmala alcoholic extracts against six pathogenic bacteria in planktonic 111of p. Assessment of the antimicrobial and antioxidant activities of. Antimicrobial effect, biofilm, peganum harmala, pathogenic bacteria. The present study compared the antimicrobial activity of ethanolic extract of peganum harmala l. Peganum harmala is used as an analgesic and antiinflammatory agent. Antibacterial activity of peganum harmala sciencedirect.
Pdf antibacterial activity of espand peganum harmala. Peganum harmala seed extracts are reported to contain alkaloids, flavonoids, and anthraquinones 21, 22. Bioassaydirected isolation and evaluation of harmine from the terrestrial plant peganum harmala l. Peganum harmala, commonly called wild rue, syrian rue, african rue, esfand, or harmel, among other similar pronunciations and spellings, is a perennial, herbaceous plant, with a woody underground rootstock, of the family nitrariaceae, usually growing in saline soils in temperate desert and mediterranean regions. Microbial biofilms have attracted interest in recent years because they have become the most important cause of nosocomial. All parts of plant are thought to be toxic and sever intoxication occurs in domestic animals. Successive petroleum ether, chloroform and methanol extracts of peganum harmala seeds were tested in vitro for their antibacterial activity. Chemical composition and antibacterial properties of peganum. Peganum harmala has been shown to have antibacterial and antiprotozoal activity, including antibacterial activity against drugresistant bacteria 7.
Pdf antibacterial activities of peganumharmala harmal. Antibacterial and antifungal activity from seed extracts of. Staphylococcus aureus and pseudomonas aeruginosa with values ranging between 70 to 100% while in case of antifungal assay wateracetone extract of seeds showed significant antifungal effect against aspergillus niger. Department of biology, faculty of science, university of hail, hail, kingdom of saudi arabia. Pdf antibacterial activity of espand peganum harmala alcoholic. Naziha chabir, hany ibrahim, mehrez romdhane, alexis valentin, beatrice moukarzel, mohamed mars and jalloul bouajila affiliation. Pdf antibacterial activities of peganumharmala harmal seeds. Synthesis of silver nanoparticles using peganum harmala. Antimicrobial activity peganum harmala harmine harmaline smoke ripe fruit. Pdf effect of repeated administration of peganum harmala. In this study, the plant peganum collected for providing its ethanolic and aquatic extract. Molecular structure of major alkaloids of peganum harmala15.
One streptococcal species of bacteria that has been attributed as the cause streptococcosis in. Materials and method agar diffusion technique and micro broth dilution method were employed to test the antimicrobial effects of these two agents on s. The total alkaloids of flower were compared with total alkaloids of ripe fruit by tlc method. International journal of infection antimicrobial activity. In vitro antibacterial activity results were summarized in table 3 of peganum harmala and its alkaloids against some pathogenic bacterial strains isolated from patients streptococcus. Chemical composition, antibacterial and phytotoxic. It is effective for the treatment of dermatosis disease 9, its leaves are used as an antinociceptive 10. Antimicrobial activity of harmal plant peganum harmala l. Results showed the ethanolic extract of peganum harmala at 0. This is because the increase in the emergence of bacterial strains resistant to multiple clinical disease. Zygophyllaceae is one of the most famous medicinal plants used in traditional medicine of iran. It is native to arid regions ranging from the eastern mediterranean to northern india, mongolia, and is present in southeast europe, including southern italy puglia and sardinia in arid steppes and sides of roads.
Third steps chemical reaction between alkaloids and hydrochloric acid. Peganum harmala, zygophyllaceae, analgesic, antiinflammatory, carrageenan. This study was planned to identify and quantify the lipid composition of sudanese peganum harmala l. The antibacterial activity of results it was revealed that the extract of p.
The antibacterial activity was evaluated by the determination of minimum inhibitory concentration mic using the solid medium technique. The root is applied to kill lice and when burned, the seeds kill insects. Peganum harmala, seed extracts, fish pathogenic bacteria, antibacterial activity. Uses, side effects, interactions, dosage, and warning. Therefore, the objectives of this study are to investigate the antibacterial activity of extracts and fractions of p. Antibacterial, muscle relaxant, and hypnotic effects of seeds. Sep 12, 2015 antibacterial activities of peganum harmala harmal seeds extract and fractions against pathogenic e. Reportedly the ancient greeks used powdered peganum harmala seeds to get rid of ta pew orm snd cu ig f v bly malaria. Antibacterial properties of methanolic extract of mentioned parts were. Previous studies demonstrated that the polyphenols such as tannins and flavonoids as epigallocatechin, catechin, myricetin. This study was aimed to examine the antibacterial activities of peganum harmala extracts on the. Antibacterial activities of peganumharmala harmal seeds. Peganum harmala smoke from the seeds kills algae, bacteria, intestinal parasites and molds. In vitro antibacterial activity results were summarized in table 3 of peganum harmala and its alkaloids against some pathogenic bacterial strains isolated from patients streptococcus, staphylococcus, aeromonas, li, klebsiella, acinetobacter.
The methanolic fraction was found to be most effective against all tested microorganisms. Antibacterial activities of peganumharmala harmal seeds against pathogenic e. Antioxidant, antimicrobial and antileishmanial study of. The plant is used traditionally as an emmenagogue and an abortifacient agent in the middle east and north africa.
Chemical composition and antibacterial properties of. Green synthesis of assembled silver nanoparticles in nano. Antibacterial, muscle relaxant, and hypnotic effects of. Green synthesis of assembled silver nanoparticles in nano capsules of peganum harmala l leaf extract. Digestive and nervous syndromes have been observed in animals that consume sublethal amount of the plant. Antibacterial and antifungal activities of betacarboline alkaloids of peganum harmala l seeds and their combination effects. During last decades, there has been a steady growth of. In vitro antibacterial activity of peganum harmala iranian journal of. Introduction inflammation is the response to injury of cells and body tissues through different factors such as infections, chemicals. Synthesis of silver nanoparticles using peganum harmala extract as a green route matin azizi a, sajjad sedaghat b, kambiz tahvildari a, pirouz derakhshi a and ahad ghaemi c a departmentofchemistry,collegeofscience,northtehranbranch,islamicazaduniversity,tehran,iran.
Ethyl acetate, chloroform, butanol and methanol extracts of the leaves of peganum harmala were tested for antibacterial, antioxidant and antiviral activities. Antibacterial and antifungal activity from seed extracts of peganum harmala, international journal of advance research, ideas and innovations in technology, apa jayaprakash chinnappan, veeran mohanraj 2016. Experimental and computational study of biological. The present study was carried out to determine the potential antibacterial effect of ethanol extracts of p. Pegnum harmala, alkaloids, phytochemical, antibacterial activity and isolated. Antibacterial and antifungal activity from seed extracts. The present study investigated the antimicrobial activity of harmal peganum harmala aqueous extracts against two fungi aspergillus niger and penicilium italicum and two gram negative bacteria escerichia coli and salmonella typhi. Peganum harmala has antibacterial activity, including antibacterial activity against drugresistant bacteria.
Darabpour ee, poshtkouhian ba, motamedi h, mansour s, nejad s 2011 antibacterial activity of different parts of peganum harmala l. Bioassaydirected isolation and evaluation of harmine from. Antibacterial activities of peganum harmala harmal seeds extract and fractions against pathogenic e. Experimental and computational study of biological activities of alkaloids isolated from peganum harmala seeds f. The present study investigated the antimicrobial activity. Harmal peganum harmala is a plant of the family nitrariaceae, native from the eastern mediterranean region east to india. Gc ms analysis of the fixed oil revealed the presence of. Dec, 2017 darabpour ee, poshtkouhian ba, motamedi h, mansour s, nejad s 2011 antibacterial activity of different parts of peganum harmala l. Root extract on isolated rat small intestine, authoramjad t. Antibacterial activity of different parts of peganum harmala.
The present study was conducted to investigate antibacterial properties of fruit and flower of peganum harmala. Several studies have evaluated the antibacterial activities of the p. Antibacterial activity of different parts of peganum harmala l. Chloroformic and methanolic extracts represented significant antibacterial activity on grampositive bacteria rather than gramnegative bacteria, with mic values ranging between 0. Collection and identification of plant materials the plant peganumharmala seeds alharmal was. It is also used as an anthelmintic to expel parasitic worms. The objective of this work is insufficient information on the study of plants p. Study of the chemical components of peganum harmala and. Antibacterial activity of different parts of peganum. Peganum harmala, fluoresces under ultraviolet light. It also inhibits the reproduction of the tribolium castaneum beetle. Antibacterial activity of espand peganum harmala alcoholic.
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